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IJSTR >> Volume 9 - Issue 1, January 2020 Edition

International Journal of Scientific & Technology Research  
International Journal of Scientific & Technology Research

Website: http://www.ijstr.org

ISSN 2277-8616

Endothelial Dysfunction As A Predictor Of Changes In System A Mother-Placenta-Fetus At The Complicated Pregnancy Gulchekhra Tastanova

[Full Text]



Tashkent State Dental Institute



vascular endothelium, angiogenesis, vascular endothelial growth factor, nitric oxide, hypochromic anemia, gestosis.



Were elucidate changes in the NO content, eNOS and iNOS activity, ONO2‾, VEGF,VEGFR-2 rate in the placenta and umbilical cord blood of a newborn after pregnancy with hypochromic anemia and gestosis. In pregnancy, complicated by gestosis and hypochromic anemia, unidirectional disturbances in the NO-system are noted - inhibition of e-NOS activity against the background of NO, i-NOS and ONO2‾expression. The development of DEP in the mother-placenta-fetus system is combined with the expression of ET-1, VEGF and its VEGFR-2 receptor, which can cause the development of structural disorders in the placenta, disorders of angiogenesis in it and as a consequence the development of placental insufficiency, pre – and postnatal fetal pathology.



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