A Pilot Study Of Microsporidiosis And CD4 T-Cells In North- Central, Nigeria
Yako AB, Ajayi OO, Lar P, Chessed G, Auta KI,
Keywords: Pilot. Microsporidiosis. CD4. T- cells. North-central.
Abstract: Two species of Microsporidia were identified (Enterocytozoon bieneusi and Encephalitozoon cuniculi) among the non-HIV, and immunocompromised individuals at the Jos, Plateau and Benue State, Nigeria. In Jos, 500 species were subjected to laboratory test and the infection rate of microsporidium species were 1(0.5%) for gastroenteritis with <350 cell/Ál; 15(15.0%) were HIV individuals with <200 cell/ Ál, and 19(19.0%) AIDS patients had low CD4 counts (<100 cell/ Ál). The severity of the illness was seen to have impact on the CD4 counts of the individuals in Makurdi where, in both sexes 5(3.5%) students had <100 cells/ Ál CD4 counts with corresponding fall in 36(5.7%) Civil servants of <100 cells/ Ál cells count. Housewives were 44(8.8%) with <50 cells/ Ál, and others (undefined occupational status) 11(1.5%) had CD4 counts <90 cell/ Ál. Microsporidiosis is now known to cause a serious threat in HIV/AIDS patients in Nigeria with less pathogenesis among non-HIV individuals hence, P<▒1.96 critical region, we accept that, there was a significant difference in the distribution of Microsporidiosis among sexes in Makurdi with the x2=0.59<7.8 at 5% level of significance (indicating a significant difference in sex related prevalence at the Jos, Plateau). However, there was high level of social behavior observed at Makurdi with a general low CD4 counts (<50 cell/ Ál-<100 cell/ Ál).
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