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IJSTR >> Volume 8 - Issue 3, March 2019 Edition



International Journal of Scientific & Technology Research  
International Journal of Scientific & Technology Research

Website: http://www.ijstr.org

ISSN 2277-8616



Development of Instant Granules Containing Sappan Wood (Caesalpinia sappan L) and Temu Mangga (Curcumma mangga Valeton & Zipp) Extract Combination as Antimotility

[Full Text]

 

AUTHOR(S)

Trisna Permadi, Swasono R. Tamat, Kartiningsih

 

KEYWORDS

 

ABSTRACT

Indonesia is one of countries which as plants that have medicinal properties. Sappan wood (Caesalpinia sappan L) and temu mangga (Curcumma mangga Valeton & zipp) are native plants to Indonesia, which have antimotility property. Sappan wood and temu mangga contains flavonoids, saponins, tannins, steroids / triterpenoids and volatile oil which considered provide antimotility activity. This study begins with the maseration using ethanol 70% then evaporated and spray dryed. The various ratio of extract combination were formulated into instant granules. The granules were tested for phisicochemical properties and hedonic score, and the antimotility activity using colonic transit time method. All the granules complied with the phisicochemical properties of granules and the hedonic score. The best antimotility activity obtained in granules containing sappan wood and temu mangga extract 21:9, with intestinal transit percentage (60,07%) did not significantly different from the normal control (ANOVA one-way unstacked at α = 0,05).

 

REFERENCES