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IJSTR >> Volume 4 - Issue 4, April 2015 Edition



International Journal of Scientific & Technology Research  
International Journal of Scientific & Technology Research

Website: http://www.ijstr.org

ISSN 2277-8616



Effect Of Polyphenols Klika Ongkea (Mezzetia Parviflora Becc) Against Blood Glucose Wistar Rats Induced By Streptozotocin

[Full Text]

 

AUTHOR(S)

Jangga, Rosdiana Natsir, Suryani As’ad , Agussalim Bukhari

 

KEYWORDS

Keywords: blood glucose, polyphenols, streptozotocin.

 

ABSTRACT

Abstract: When this has been developed medicines from natural ingredients to control diabetes mellitus, most of these materials have been studied and shown to be effective as an alternative therapy. This study aimed to determine the effect of polyphenols Klika ongkea (Mezzetia parviflora Becc.) To decrease blood glucose levels induced streptozotosin wistar rats (STZ) and to determine the concentration of how the effect is not significantly different from the control group of drugs. In this study used Wistar rats were 120 tails are divided into six treatment groups, the first group of healthy controls were given Na. CMC 1%, group II were given pain control STZ 40 mg / kg body weight of mice, group III was given the drug control galvus (vildagliptin), group IV, V and VI are given polyphenols Klika ongkea each 100mg / kg and 300mg / kg for 21 day. The results showed that administration of polyphenols Klika ongkea 300mg / kg body weight of rats and 300 mg / kg body weight of mice as a protective effect on the decreased levels of blood glucose Wistar rats induced by STZ and giving polyphenols Klika ongkea 300mg / kg body weight of rats and 300 mg / kg rat as protective effect was not significantly different the effect of galvus (vildagliptin) 0.9 mg / 200 gBW mice.

 

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