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IJSTR >> Volume 9 - Issue 4, April 2020 Edition

International Journal of Scientific & Technology Research  
International Journal of Scientific & Technology Research

Website: http://www.ijstr.org

ISSN 2277-8616

Hepatorenal Histological Studies On Bacterial Probiotic Treated Colitis Induced Male Albino Wistar Rats

[Full Text]



Shalini Gnanam, T., Kolanchinathan, P., Rathnakumari, P., Balasundaram, A.



Bacillus, colitis, DSS, histology, kidney, liver, Probiotics



Ulcerative colitis is an inflammatory bowel disease due to the various reasons. The available chemical therapies are curing the UC temporarily and provoking the disease with more severe aggressive form. Nowadays as an alternative measure, probiotics are used to treat UC without destroying the beneficial microflora in host. Male albino wistar rats were treated with 5% DSS for colitis induction. Histological analysis of hepatic and renal tissues of DSS colitis induced rats showed deleterious damages along with inflammation and blood vessel congestion. Group III (DSS+Probiotic) showed reformed layers with reduced inflammation in glomerulus and hepatocyte regions. This study proved that the oral administration of probiotics, cured the inflammation in DSS colitis wistar rats.



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