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IJSTR >> Volume 8 - Issue 7, July 2019 Edition



International Journal of Scientific & Technology Research  
International Journal of Scientific & Technology Research

Website: http://www.ijstr.org

ISSN 2277-8616



Antimicrobial And Phytochemical Potential Of Chenopodium Album Linn.

[Full Text]

 

AUTHOR(S)

Rashi Saini, Dinesh Kumar, Amita Mittal

 

KEYWORDS

Phytochemical, antioxidant, antimicrobial, P. aeruginosa, C.album.

 

ABSTRACT

Chenopodium album Linn. (Family: Chenopodiaceae) is a wildly growing weed in Africa, Asia, Europe and North America. In folk medicine, this plant has been used as antiparasitic, diuretic, hepato-protective, laxative and sedative. Its leaves possesses antirheumatic, anthelmentic, antiphlogistic, mildly laxative and odontalogic properties, applied as wash or poultice to bug bites, rheumatic joints, sunstroke, and swollen feets. This plant is used as vegetable in India and has high biological potential in addition to basic nutritional benefits. Previous scientific studies have reported the anthelmintic, antipruritic, contraceptive and sperm immobilizing properties of this plant. Hence, this plant possesses a great potential for detailed biological screening. So, in order to elucidate the potential traditional use of this plant, the present study was undertaken to evaluate its phytochemical and antimicrobial screening along with its free radical scavenging effect. Phytochemical investigations confirmed the presence of alkaloids, flavonoids, anthocynidine, saponins, glycosides, tannins and carbohydrates in the plant leaves extract. Antimicrobial effect tested by well diffusion method proved that methanolic leaf extract of the plant possesses considerable inhibitory activity against Escherichia coli, Pseudomonas aeruginosa, Bacillus subtilis, Candida albicans, and Candida glabrata.The antioxidant activity was studied by DPPH free radical scavenging activity, total phenolics content and ascorbic acid estimation. The decolorization of purple colour in DPPH assay indicated the free radical scavenging activity. This activity was dose dependent and maximum activity (80.58%) was observed 50 µg/ ml. The total phenolic content in C. album is found to be 0.115g of phenols, and is calculated by plotting O.D. on standard graph of catechol. The ascorbic acid in leaf extract of C. album is calculated as 1.29 mg of ascorbate / g of leaf. Total phenolic content and ascorbic acid in the leaf extract justify the nutritional and biological significance of C. album.

 

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