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IJSTR >> Volume 6 - Issue 10, October 2017 Edition



International Journal of Scientific & Technology Research  
International Journal of Scientific & Technology Research

Website: http://www.ijstr.org

ISSN 2277-8616



Synthesis Of 3-Substituted-6, 8-Dibromo-2-Methyl Quinazolin-4(3H)-One Derivatives Via 6, 8-Dibromo-2-Methyl-4h-Benzo [D] [1,3] 朞xazin-4-One.

[Full Text]

 

AUTHOR(S)

Osarumwense, P.O, Edema, M.O, Usifoh, O, Marvis, E.

 

KEYWORDS

benzoxazinone, cylization, 3, 5-dibromoanthranilate, 6, 8-dibromo-2-Methyl-4H-benzo[d] [1, 3] 杘xazine-4-one, nitrogen nucleophile, synthesis, 3-substituted-6,8-dibromo-2-Methyl-quinazoline4(3H)-one.

 

ABSTRACT

The condensation of methyl 3, 5-dibromoanthranilate with acetic anhydride yielded the cyclic compound 2-Methyl-6, 8-dibromo-4H-benzo-oxazine-4-one which further produce a novel 2, 3-disubstituted quinazolin-4-ones via the reaction with hydrazine hydrate. The compounds synthesized were unequivocally confirmed by means of infrared, Nuclear Magnetic Resonance (1H and 13C), Gas chromatography Mass Spectrophotometer and Elemental analysis.

 

REFERENCES

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[7] Corresponding Author; E-mail address; osarodqion.peter@yahoo.com

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