Over 27% of Type II Diabetic Patients Studied at Parirenyatwa Diabetic Clinic in Zimbabwe Have Evidence of Impaired Renal Function
Erisi Mafuratidze, Kurai Chako, Heather Phillipo, Danai Tavonga Zhou
Index Terms: Creatinine, Diabetics, Parirenyatwa, Renal Function, Type II Diabetes mellitus, Urea, Zimbabwe
Abstract: Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia and is the most prevalent non communicable disease in the world. Progressive kidney damage is one of the major complications of diabetes mellitus and has significant mortality and morbidity. The aim of our study was to analyze renal function in Type II diabetics that have been on treatment for more than 12 months. Our laboratory based cross-sectional study was done on 239 patients who have been diagnosed as Type II diabetics for more than 12 months, who routinely attend the Parirenyatwa Diabetic Clinic. Serum sample were used for urea and creatinine analysis. Of the 239 patients studied, 65 (27.2 %) were found to have elevated values of creatinine and/or urea. Creatinine is usually elevated when the kidneys have lost about 50% of their function. Therefore, the prevalence of impaired renal function found in patients attending Parirenyatwa Diabetic clinic was approximately 27.2%. All patients with impaired renal function were hypertensive. Males had a greater percentage of elevated urea and creatinine levels compared to females. Age and period on treatment were found to be significantly associated with impairment of renal function.
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