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IJSTR >> Volume 7 - Issue 10, October 2018 Edition



International Journal of Scientific & Technology Research  
International Journal of Scientific & Technology Research

Website: http://www.ijstr.org

ISSN 2277-8616



Produce Active Sunscreen Gel By Extracting Etil Acetate Fraction And Nanoparticles Fraction Etil Asetat From Jatropha Curcas Linn

[Full Text]

 

AUTHOR(S)

Dewi Rahma Fitri, Partomuan Simanjuntak, Deni Rahmat

 

KEYWORDS

chitosan, ionic gelation, SPF gel.

 

ABSTRACT

The exposure to excessive and long lasting sun can cause adverse effects on the skin of erythema and even skin cancer. Jatropha curcas Linn is one of the plants that have potential substants to protect skin from the adverse effects of UV rays. Sunscreen preparations derived from ethyl acetate fractions of Jatropha leaves are made. Ethyl acetate fraction of Jatropha leaves has IC50 value of 43 ppm potency to be used as sunscreen preparation. To increase the value of SPF, the ethyl acetate fraction of Jatropha leaves is made in the form of nanoparticles formulated into gel preparation. Ethyl acetate fraction of Jatropha leaves was made in the form of nanoparticle extract using 0.2% chitosan and 0.1% NATPP with a 5: 1 volume ratio with ionic gelation method. The results obtained fulfill the requirements include spherical morphology, particle size 300.2 nm and potential zeta value 39.54 mV. Based on the result of this research, it can be concluded that ethyl acetate fraction and nanoparticle extract of ethyl acetate fraction of jatropha leaves can produce sunscreen gel using carbopol ultrez 10 (0,5%) as gelling agent with concentration of each active substance 0, 1% using a homogenizer tool at 200 rpm for 60 minutes. it has obtained value of SPF 7 for gel of ethyl acetate of Jatropha leaves and SPF value 12 for gel Nano extract of ethyl acetate fraction of Jatropha leaves.

 

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