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IJSTR >> Volume 8 - Issue 10, October 2019 Edition



International Journal of Scientific & Technology Research  
International Journal of Scientific & Technology Research

Website: http://www.ijstr.org

ISSN 2277-8616



Evaluation Of Aphrodisiac Activity Of Allium Sativum In Male Rats

[Full Text]

 

AUTHOR(S)

Pooja V Warange, Saravanan J, Praveen T K, Emdormi Rymbai, Deepa S

 

KEYWORDS

Acute toxicity, Allium sativum, aphrodisiac, nitric oxide, sexual behaviour, sexual dysfunction, sperm count,

 

ABSTRACT

The aim of the current study is to evaluate the aphrodisiac activity of petroleum ether extract of Allium sativum. The plant material was extracted with petroleum ether, chloroform, ethyl acetate and methanol using soxhlet apparatus. All the extracts were subjected to nitric oxide assay to determine the effect of different extracts on NO production. The maximum effect was shown by petroleum ether extract in nitric oxide assay. Based on this observation, petroleum ether extract was selected for further in-vivo aphrodisiac studies. The aphrodisiac activity of petroleum ether extract of Allium sativum was evaluated in male wistar rats through sexual behaviour tests and sperm count. A significant change was observed in behavioural tests and an increase in sperm count was also observed in test group as compared to the control group. The results of the current study prove the aphrodisiac property of petroleum ether extract of Allium sativum.

 

REFERENCES

[1] Male A, Dysfunction S, Force T, Cunningham GR, Goodman NF, Nankin HR, et al. American association of clinical endocrinologists medical guidelines for clinical practice for the evaluation and treatment of male sexual dysfunction: A couple’s problem - 2003 update. Endocr Pract 2003;9:77–94.
[2] Majewski M. Rocz Panstw Zakl Hig 2014;65(1):1-8 Allium sativum: facts and myths regarding human health 2013;65:1–8.
[3] Anuthakoengkun A, Itharat A. Inhibitory effect on nitric oxide production and free radical scavenging activity of Thai medicinal plants in osteoarthritic knee treatment. Journal of the Medical Association of Thailand= Chotmaihet thangphaet. 2014 Aug;97:S116-24.
[4] Pande M, Pathak A. Aphrodisiac activity of roots of Mimosa pudica Linn. ethanolic extract in mice. Int J Pharm Sci Nanotechnol. 2009 Apr;2(1):477-86.
[5] A. Of, D. Use, P. Using, A.T. Debremarkos, R. Hospital, International Journal of Innovative Pharmaceutical Sciences and Research at Debremarkos Referral Hospital , northwest, 2 (2014) 1270–1288.
[6] R. Singh, A. Ali, G. Jeyabalan, A. Semwal, Jaikishan, An overview of the current methodologies used for evaluation of aphrodisiac agents, J. Acute Dis. 2 (2013) 85–91. doi:10.1016/s2221-6189(13)60105-5.
[7] A. Abedi, M. Parviz, S.M. Karimian, H.R.S. Rodsari, Aphrodisiac Activity of Aqueous Extract of <i>Phoenix dactylifera</i> Pollen in Male Rats, Adv. Sex. Med. 03 (2013) 28–34. doi:10.4236/asm.2013.31006.
[8] S. Ramachandran, Y. Sridhar, S.K.G. Sam, M. Saravanan, J.T. Leonard, N. Anbalagan, S.K. Sridhar, Aphroidisiac activity of Butea frondosa Koen. ex Roxb. extract in male rats, Phytomedicine. 11 (2004) 165–168. doi:10.1078/0944-7113-00343.
[9] H. Guohua, L. Yanhua, M. Rengang, W. Dongzhi, M. Zhengzhi, Z. Hua, Aphrodisiac properties of Allium tuberosum seeds extract, J. Ethnopharmacol. 122 (2009) 579–582. doi:10.1016/j.jep.2009.01.018.
[10] M.J. Luthfi, A Simple and Practical Method for Rat Epididymal Sperm Count (Rattus norvegicus), Biol. Med. Nat. Prod. Chem. 4 (2015) 1. doi:10.14421/biomedich.2015.41.1-3.
[11] M. Ali, K.K. Al-Qattan, F. Al-Enezi, R.M.A. Khanafer, T. Mustafa, Effect of allicin from garlic powder on serum lipids and blood pressure in rats fed with a high cholesterol diet, Prostaglandins Leukot. Essent. Fat. Acids. 62 (2000) 253–259. doi:10.1054/plef.2000.0152.
[12] Ku DD, Wu HC. Mechanisms of Garlic Extract-induced Pulmonary Vasorelaxation: Role of Allicin and its related Organosulfur Metabolites.