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IJSTR >> Volume 3- Issue 11, November 2014 Edition



International Journal of Scientific & Technology Research  
International Journal of Scientific & Technology Research

Website: http://www.ijstr.org

ISSN 2277-8616



Antimicrobial Activities Of Synthesized Zinc(II) Mixed-Ligand Complexes Derived From 2-Acetylpyridine-4-Phenylsemicarbazone And Nitrogen-Sulphurmonodentate Ligands

[Full Text]

 

AUTHOR(S)

G. E. Iniama, E. N. Nfor, E. D. Okon, I. T. Iorkpiligh

 

KEYWORDS

Keywords: mixed ligands, Zinc(II) 2-acetylpyridine-4-phenylsemicarbazone, complexes, semicarbazone, tetrahedral geometry, antimicrobial, activity,

 

ABSTRACT

Abstract: The reaction of zinc chloride with 2-acetylpyridine-4-phenylsemicarbazone and nitrogen–sulphurmonodentate ligands such as thiophene, pyridine, picoline ,aniline and ammonia; yielded five novel mixed -ligand complexes: Zn(2-Ac.4-Psc.Th)Cl2 ,Zn(2-Ac.4-Psc.Py)Cl¬2, Zn(2-Ac.4-Psc.Pi)Cl2, Zn(2Ac.4-Psc.An)Cl2 and Zn(2-Ac.Psc.Am)Cl2. These were characterized by elemental analysis,molar conductivity,1H and 13C-NMR, IR and electronic absorption spectroscopic studies.All the complexes possess tetrahedral geometries. The antimicrobial activities were evaluated against staphylococcus aureus, Bacillus anthracis,Aspergillusnigers andCandida albicans.The result of significant inhibition of growth and proliferation of these microbes by the chelates were obtained particularly with the highest efficiency shown by thethiophene and aniline incorporated complexes

 

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