Review Of Consultations For Children With Sickle Cell Disease (CHR Kenitra Morocco)
Mouden Samira, Ahami Ahmad Omar, Mouilly Mustapha, Fayez Noureddine, Hajji Ahmad
Index Terms: Keywords: child, sickle cell crises, Environment, socio-economic determinants region gharb Chrarda benihssen, pediatrics.
Abstract: Also called sickle cell anemia Sickle cell anemia is a genetic disease of autosomal recessive linked to abnormal structure of the hemoglobin which leads to the formation of hemoglobin S (HbS). The descriptive and cross that we conducted at the pediatric ward of the regional hospital Gharb study Chrarda benihessen Kénitra we were enjoying a work force of 164 children with sickle cell disease over a period of twenty four months ( from June 2010 to June 2012 ) . On average seven to eight (7-8) new cases per year. The majority of these children admitted to the exhibit acute complications that are typically associated either to a chronic hemolytic anemia, vaso -occlusive crisis, acute chest syndrome, or severe infections, which aims to identify factors likely to play a role in the occurrence of the sickle cell crises. This can cause severe functional consequences (with renal, lung, bone, etc.). In order to understand the problems and difficulties faced by sickle cell and their families in their daily lives, we have established a protocol form of a questionnaire exploring various aspects related to eating habits and lifestyle of these children. and their families, as well as family socioeconomic status, and the context of environmental life The size of the control group study consists of 60 children aged 7-14 years. Clinical and analytical information is collected from records, medical records and doctors during consultations of these patients. The results show that 71% of these children are from rural areas against 20% of children of urban origin, while 9% live in suburban area however. The majority of parents have irregular income, low educational attainment. 68% of these children use septic false in parallel they use well water in consumption and domestic use. Clinical examination and blood cell abnormalities formula revealed prevalence of 76% for fever cases painful crises severe recurrent and unpredictable also observed, as well as "acute chest syndrome " ( pneumonia or pulmonary infarction), a bone or joint necrosis unpredictable 43% for leukocytosis . As we noted the presence of diarrhea in this sample. In conclusion, the present study showed an association between the frequency of sickle cell crises especially infectious presented by the children studied and the environmental quality of family life in which the child develops.
 HAS, Syndromes major dre'panocytaires child ETDE adolescents. January 2010.
 Embury SH, Steinberg MH.Clinical considerations.In:Embury SH, Hebbel RP, Mohandas N, Steinberg MH, eds.Sickle Cell Disease. Basic Principles and Clinical Practice. RavenPress 1994: 505-73.
 Assimadi K. Sickle. School sports and crafts. Family and Development, 1990; 57: 15-6.
 Zohoun I. Drépanocytose et santé publique. Famille et Développement, 1991
 Pollack CV. cell disease. HematolOncolEmerg 1993; 11 :365-78.
 Labie D, Elion J. Genetics and pathophysiology of sickle cell disease in LaDrépanocytose editions John LibbeyEurotext, 2003 (dir Girot R., Begue P., F. Galacteros.): 1 12.
 The nouhoum TraoreLa sickle cell child Internal holder hospitals at Gabriel Toure Hospital: Bamako (Mali) on Jun 19, 2013.
 Azzawi FZ Ahami AOT Khadmaoui A., 2008, the relationship between socio-economic, environmental and malnutrition: Case of children aged 6 to 8 years in the Gharb plain (Northwest Moroccan), Antropo 17
 Bennasser L., 1997 Diagnosis of the state of the environment in the Gharb plain: followed by the macro-pollution and its impact on the hydrochemical and biological quality of low Sebu. PhD thesis, Univ. Ibn Tufail, Kenitra, 177p
 Laine A. Sickle. Perspectives on an orphan disease. Paris: Karthala; 2004.
 R. Hamza (1), S. Fattoum (2), Mr. Péchevis (3), J. Cook (3), R. Girot (4) contribution to the sociological analysis of the impact of sickle cell disease in families of northern Tunisian public Health, 1999, volume 11, No. 3, p. 297-31
 Rees DC, Olujohungbe AD, Parker NE, Stephens AD, Telfer P, Wright J. Guidelines for the management of the acute painful crisis in sickle cell disease. Br J Haematol 2003;120(5):744
 HAS / S / management of sickle cell disease in children and adolescents Guidelines Department / September 2005.
 van der Dijs FP, Fokkema MR, Dijck-Brouwer DA, Niessink B, van der Wal TI, Schnog J-J, et al. Optimization of folic acid, vitamin B12, and vitamin B6 supplements in pediatric patients with sickle cell disease. Am J Hematol 2002;69(4):239-46
 Vilelam.m.s., sampaiom.s.c., costa f.f., brandalises.r.Reduce phagocytic activity mediated by C3b Fc monocyte receptors from children with sickle-cell disease.Brazilian J Med Biol Res 1989;
 Cetiner S., Akoglut.f., Klinc there., Akoglu e. Kumi m. Immunological studies in sickle cell disease: comparison of homozygote mild and severe variants.ClinImmunol Immunopatho1989; 53: 32-9.
 Hofmann M, de Montalembert M, Beaucquier Maccotta-B of VillartayP, Golse B. Post traumatic stress syndrome in children Affected by sickle cell disease and Their Parents. Am J Hematol.2007; 82: 171-2.