IJSTR

International Journal of Scientific & Technology Research

Home About Us Scope Editorial Board Blog/Latest News Contact Us
0.2
2019CiteScore
 
10th percentile
Powered by  Scopus
Scopus coverage:
Nov 2018 to May 2020

CALL FOR PAPERS
AUTHORS
DOWNLOADS
CONTACT

IJSTR >> Volume 5 - Issue 5, May 2016 Edition



International Journal of Scientific & Technology Research  
International Journal of Scientific & Technology Research

Website: http://www.ijstr.org

ISSN 2277-8616



Effect Of Clomiphene Citrate On Hematology And Serum Biochemistry Of Nigerian Indigenous Chicken

[Full Text]

 

AUTHOR(S)

Urom, Scholastica Mgbo Otu Chukwu, Ukpabi, H., Alum, Eucharia Akanele, Oko, E.C.

 

KEYWORDS

Nigerian indigenous chicken, Cocks, Clomiphene citrate, Hematology, Serum biochemistry

 

ABSTRACT

The effect of different doses of clomiphene citrate on haematology and serum biochemistry of Nigerian indigenous chicken were evaluated at the poultry Unit, Department of Animal Science and Fisheries, Abia State University, Umuahia, using 48 sexually matured (26 weeks old) local cocks, each group was divided into 4 treatment groups of 4 matured chickens, in a completely randomized design with 3 replications. Four levels of Clomiphene citrate treatments represented as T1 (0mg), T2 (10.00mg) T3 (20.00mg) and T4 (30.00mg) were administered to the birds. Haematology and Serum biochemical indices of the treated birds were determined at the end of the study. The result showed that there were significant differences (P<0.05) among the treatment groups in haematology and serum biochemical parameters except for the following parameters: hemoglobin red blood cell, mean corpuscular volume of the birds. It was concluded that the administration of Clomiphene citrate (Clomid®) led to changes in heamatology and serum biochemistry in Nigerian indigenous chicken which showed that clomiphene citrate can be considered safe for chicken. 10mg and 20mg levels of clomiphene citrate can bring about improved hematological indices of Nigeria indigenous chicken

 

REFERENCES

[1] Adenyemo, G. O., Ologhobo, A. D. and Adewbiyi, A. O. (2010). The effect of graded levels of dietary methionine on the haematology and semen biochemistry.

[2] Adiele,J.G. Audu H. O., Madu.T. andNwaogwugwu, R.O. (2005). Weather in 2005 at Umudike and its possibility impact on Root Crops production in Root Crops research Institute Animal Report for 2005 Pp 252-255.

[3] Anita, B., Moortry, M. and Vishwanathan, M. (2007). Muscle cholesterol and semen biochemical changes in broilers fed with crude rice bran oil. Int. J. Poult. Sci. 6(12):855-857.

[4] Arora, K. L. (2010). Differences in haemoglobin and packed cell volume in blood collected from different sites in Japanese quail (Coturnix japonica). Int J. Poult. Sci. 9(9): 828-830.

[5] Baker, F.J. and Silverton, R.F. (1985).Introduction to medical laboratory Technology.6th edition, Butter-Worth Publishing Company, England.Pp 725.

[6] Charles, D., Barr, W., Bell, E.T., Brown, J.B., Forthery and Loraine, J.A. (1963). Clomiphene in the treatment of oligomenorrhea and amenorrhea; Am. J. Obstet Gynecol. 86: 913-922.

[7] Greenbatt, R.B., Barfield, W.E., Jungck, E.C. and Ray, A.W. (1961). Induction of ovulation with MRL/41: Preliminary report. J.Am. Med. Assoc. 178: 101-104.

[8] Hafez, E.S.E. (1990).Artificial Insemination in Reproduction in farm Animals.(5th Ed) Lea and Fibiger, Philaelpha. Pp.481-497.

[9] Horst, (1889). Native fowl as a reservoir for genomes and genes with direct effect on adaptability and their potential for tropical oriented breeding plant: A review. Animal resource dev.33:63-79.

[10] Iheukwumere, F. C. (2005). Super Ovulation in Goats In: AfamAnene and Nwaigbo, L.C. (eds). Issues in Sustainable Agriculture in Nigeria.Osprey Publication Centre, Owerri, Nigeria. 1 – 9.

[11] Kaiser, I. H. (1963).Pregnancy following clomiphene-induced ovulation in chiari-formmel syndrome.Am. J. Obstet. Gynecol. 87: 149-151.

[12] Kolm, R.A. and Allen, M.S. (1995).Enrichment of proteolytic activity relative to Nitrogen in preparation for Rumen for in-vitro studies.Animal Food Sc.Tech’ (112): 1-4.

[13] Mohammed, A. (2010). Effect of acetylsalicylic acid (ASA) in drinking water on reproductive performance and blood characteristics of layer hens during heat stress. Int. J. Poult. Sci. 9 (4): 382-385.

[14] Obi, I. U. (1990). Statistical method of detecting differences between treatment means, 2ndedition. Snaap Press, Enugu, Nigeria

[15] Olorode, B.R. and Longe, O.G. (2000). Effect Of Replacing Palm Kernel Cake with shear cake on quality characteristics, haematology and semen chemistry of laying hens. Nigerian. J. Anim. Prod. 27:19-23.

[16] Onyeamisi, B. I. (2007). Calcium, phosphorus levels in nigeria guinea fowls. Int. J. Poult. Sci. 6(8): 610-611.

[17] Pavlak, M., Vlahovic, K., Jarcic, J., Dorc, A. and Zupanuc, Z (2005). Age, Sexual and Seasonal Differences of Haematological Values and antibody status to chlamidophila specie in feral and racing pigeons (Columba livia forma domestica) from an urban environment (Zagred, Croatia), European J. Wildlife Res. 51 (4): 271-278.

[18] Rej, R. and Hoder, M. (1983).Alanime Transaminase. In-Methods of Ezymatic Analysis 3rd Edition H.U. Bergmeyer, I. Berg Meyer and M. grassal (eds). WeinhenVelag. Chemie 1:3416-433.

[19] Riley G M and Evans T N (1964). Effects of clomiphene on an ovulatory ovarian functions; Am.J. Obstet. Gynecol. 89 97-110.

[20] RIM (Resources Inventory and Management Ltd) (1992). Nigeria National Livestock Survey, Federal Department of Livestock and Pest Control Services, Abuja, Nigeria.Pp. 287.

[21] Steel, R.G.D. and Torrie, J.H. (1980).Principles of procedure of statistic and biometric.

[22] Whitelaw M.J (1963). Clomiphene CITRATEe: Newer aspects of its use in prevention and treatment of infertility; Fertil. Steril. 14 540-546

[23] Zhou, W. T., Fujita M and Tammamto S. (1999). Termoregulatory Responses and Blood Viscosity in Dehydrated Heat Exposed Broilers (Gallus domesticus). J. Thermal. Biol. 24 (3): 185-192