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IJSTR >> Volume 5 - Issue 5, May 2016 Edition



International Journal of Scientific & Technology Research  
International Journal of Scientific & Technology Research

Website: http://www.ijstr.org

ISSN 2277-8616



Sample Preparation In Bioanalysis: A Review

[Full Text]

 

AUTHOR(S)

Anjana Vaghela, Ashok Patel, Ajay Patel, Amit Vyas, Nilesh Patel

 

KEYWORDS

Bioanalysis, Liquid chromatography mass spectrometry, Solid phase extraction, Liquid-Liquid extraction, Precipitation

 

ABSTRACT

Bioanalysis is sub-discipline of analytical chemistry covering the quantitative measurement of drugs and their metabolites in biological systems. Whereas Liquid chromatography mass spectrometry is a technique which is widely used for the quantification of drug from biological fluid. This article reviews the most recent advances in sample preparation, separation analysis and different type of cartridge used in analysis of biological fluid. Further, this paper also discuss about the merits and demerits of solid phase extraction (SPE), liquid-liquid extraction (LLE) and precipitation.

 

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